Cardiovascular genome phenome study

Grants | American Heart Association

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Artificial Intelligence and Machine Learning Grants. Build, test and refine artificial intelligence and machine learning algorithms using varying data sources, which may include, images, electronic health records, wearable devices, smart phones and other sensor-related technology, genetics, biology, and community engagement metrics.

Grants | American Heart Association

American Heart Association Cardiovascular Genome-Phenome Study

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The American Heart Association has established the Cardiovascular Genome-Phenome Study (CV-GPS) as a means by which to achieve the goal of using modern genomics and phenotyping optimally to combat cardiovascular disease (CVD).

American Heart Association Cardiovascular Genome-Phenome Study

American Heart Association Cardiovascular Genome-Phenome Study

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1/6/2015 · The American Heart Association has established the Cardiovascular Genome-Phenome Study (CV-GPS) as a means by which to achieve the goal of using modern genomics and phenotyping optimally to combat cardiovascular disease (CVD). CVD remains the leading cause of …

American Heart Association Cardiovascular Genome-Phenome Study

American Heart Association Cardiovascular Genome-Phenome Study

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Genome-wide admixture and association study of serum iron, ferritin, transferrin saturation and total iron binding capacity in African Americans [published online ahead of print September 15, 2014]. Hum Mol Genet . doi: 10.1093/hmg/ddu454.

American Heart Association Cardiovascular Genome-Phenome Study

American Heart Association Cardiovascular Genome-Phenome Study

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The American Heart Association has established the Cardiovascular Genome-Phenome Study (CV-GPS) as a means by which to achieve the goal of using modern genomics and …

American Heart Association Cardiovascular Genome-Phenome Study

American Heart Association Cardiovascular Genome-Phenome ...

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Cardiovascular Genome-Phenome Study (CV-GPS) as a means by which to achieve the goal of using modern genom-ics and phenotyping optimally to combat cardiovascular disease (CVD). CVD remains the leading cause of death in the United States and has become a major cause of morbidity and mortal-

American Heart Association Cardiovascular Genome-Phenome ...

American Heart Association Cardiovascular Genome-Phenome ...

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American Heart Association Cardiovascular Genome-Phenome Study (CVGPS) Heart Failure Discovery Grant Supported by AstraZeneca This is an award for innovative projects that can address questions of high impact as outlined herein.

American Heart Association Cardiovascular Genome-Phenome ...

Cardiovascular Genome-Phenome Study 2016 - News on Heart.org

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This is a series about Cardiovascular Genome-Phenome Study Discovery grants awarded by the American Heart Association to speed personalized treatments and prevention for heart disease.

Cardiovascular Genome-Phenome Study 2016 - News on Heart.org

The Framingham Heart Study: Laying the Foundation for ...

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Framingham joins the NIH's Jackson Heart Study and the American Heart Association to form a new collaboration on cardiovascular population science: the Cardiovascular Genome-Phenome Study. 30 2017 Whole genome sequencing is completed in 4,200 . Framingham participants. 31

The Framingham Heart Study: Laying the Foundation for ...

Cardiovascular Genome-Phenome Study 2015 - News on Heart.org

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Ramy Arnaout is studying the link between antibodies, cardiovascular diseases and aging. 6: How food and genes interact to influence heart disease Dr. Simin Liu is investigating how dietary factors may interact with a person’s genome to contribute to heart disease and Type 2 diabetes. 7:

Cardiovascular Genome-Phenome Study 2015 - News on Heart.org

An Introduction to CV-GPS: the Cardiovascular Genome ...

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1/30/2015 · An Introduction to CV-GPS: the Cardiovascular Genome-Phenome Study ... Chair CVGPS Science Oversight Committee, introduces the American Heart Association's Cardiovascular Genome Phenome Study ...

An Introduction to CV-GPS: the Cardiovascular Genome ...

American heart association cardiovascular genome-phenome ...

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American heart association cardiovascular genome-phenome study foundational basis and program Ivor Benjamin , Nancy Brown, Gregory Burke, Adolfo Correa, Steven R. Houser, Daniel W. Jones, Joseph Loscalzo, Ramachandran S. Vasan, Gayle R. Whitman

American heart association cardiovascular genome-phenome ...

Jackson Heart Study > Home

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In addition to independent investigator-initiated collaborations that may or may not involve multiple sites or cohorts, the Jackson Heart Study (JHS) is participating in several multi-site and cross-cohort collaborations, including JHS Vanguard Centers, JHS Working Groups, the American Heart Association Cardiovascular Genome Phenome Study (AHA CVGPS), and NHLBI Trans Omics for Precision ...

Jackson Heart Study > Home

American Heart Association Cardiovascular Genome Phenome ...

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American Heart Association Cardiovascular Genome Phenome Study (CVGPS) Applications for Grants . The American Heart Association (AHA) is a non-profit, voluntary health organization funded by private contributions. The mission of the American Heart Association is to build healthier lives, free of cardiovascular disease and stroke.

American Heart Association Cardiovascular Genome Phenome ...

A Genome- and Phenome-Wide Association Study to Identify ...

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A Genome- and Phenome-Wide Association Study to Identify Genetic Variants Influencing Platelet Count and Volume and their Pleiotropic Effects ... This variant has been previously noted to be associated with cardiovascular diseases including myocardial infarction and ... using electronic medical records for genome- and phenome-wide studies ...

A Genome- and Phenome-Wide Association Study to Identify ...

American Heart Association Cardiovascular Genome-Phenome ...

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Version of Record. American Heart Association Cardiovascular Genome-Phenome Study: Foundational Basis and Program

American Heart Association Cardiovascular Genome-Phenome ...

Genome-wide association study - Wikipedia

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In genetics, a genome-wide association study (GWA study, or GWAS), also known as whole genome association study (WGA study, or WGAS), is an observational study of a genome-wide set of genetic variants in different individuals to see if any variant is associated with a trait.

Genome-wide association study - Wikipedia

About Leadership | American Heart Association

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In 2013, the American Heart Association Board of Directors made a commitment to advance precision cardiovascular medicine. The initial platform launched as the Cardiovascular Genome-Phenome Study (CVGPS) before it evolved into the AHA Institute for Precision Cardiovascular Medicine.

About Leadership | American Heart Association

Information on the Institute for Precision Cardiovascular ...

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Our first foray into the precision medicine arena was built around the Cardiovascular Genome-Phenome Study (CVGPS). Through this program, the American Heart Association (AHA) spearheaded a collaborative effort to accelerate the future of cardiovascular medicine. Through three award mechanisms the CVGPS program combines the power of long-term ...

Information on the Institute for Precision Cardiovascular ...

A phenome-wide association study to discover pleiotropic ...

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2/11/2019 · A phenome-wide association study to discover pleiotropic effects of PCSK9 , APOB , and LDLR ... and appear to lower the risk of atherosclerotic cardiovascular ... the human genome-phenome ...

A phenome-wide association study to discover pleiotropic ...

Framingham Heart Study: past, present and future ...

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12/21/2015 · The Framingham Heart Study (FHS) is widely recognized for its lasting contributions to cardiovascular epidemiology. In this article we review the study’s history, past accomplishments, current research agenda and future research directions. Where we came from

Framingham Heart Study: past, present and future ...

Gayle R. Whitman's research works | American Heart ...

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The American Heart Association has established the Cardiovascular Genome-Phenome Study (CV-GPS) as a means by which to achieve the goal of using modern genomics and …

Gayle R. Whitman's research works | American Heart ...

Phenome - an overview | ScienceDirect Topics

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Phenome centers, such as those already established and operationalized at Imperial College London, United Kingdom, as well as at Nanyang Technological University in Singapore and Chang Gung University in Taiwan, were built to develop large-scale broad and deep metabolic phenotyping capacity and are dedicated to the study of population-level ...

Phenome - an overview | ScienceDirect Topics

Unravelling the human genome–phenome relationship using ...

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2/15/2016 · A genome- and phenome-wide association study to identify genetic variants influencing platelet count and volume and their pleiotropic effects. ... and cardiovascular disease. ...

Unravelling the human genome–phenome relationship using ...

From Genome-Wide Association Study to Phenome-Wide ...

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Chapter Seven - From Genome-Wide Association Study to Phenome-Wide Association Study: ... cardiovascular disease (CVD), type-2 diabetes (T2D), and metabolic syndrome ... Genetics, Heritability, and Genome-Wide Association Study of Obesity 47,82–84.

From Genome-Wide Association Study to Phenome-Wide ...

A genome- and phenome-wide association study to identify ...

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/ A genome- and phenome-wide association study to identify genetic variants influencing platelet count and volume and their pleiotropic effects. In: Human Genetics. 2014 ; Vol. 133, No. 1. pp. 95-109.

A genome- and phenome-wide association study to identify ...

Phenome-wide association study identifies marked increased ...

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4/10/2018 · One method to harness the power of the longitudinal, clinical data in the EHR is the phenome-wide association study (PheWAS). Similar to the way a genome-wide association study (GWAS) scans across the genome, a PheWAS scans across …

Phenome-wide association study identifies marked increased ...

Invited Commentary: The Framingham Offspring Study—A ...

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5/23/2017 · In 3 long-term prospective studies (the Atherosclerosis Risk in Communities Study, the Women's Genome Health Study, and the Malmö Diet and Cancer Study) with a total of more than 50,000 participants, both genetic and lifestyle factors were independent predictors of …

Invited Commentary: The Framingham Offspring Study—A ...

Genome- and phenome-wide analyses of cardiac conduction ...

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The phenome-wide association study approach implicated sodium channel variants modulating QRS duration in subjects without cardiac disease as predictors of subsequent arrhythmias. KW - Atrial fibrillation. KW - Electronic health records. KW - Genetics. KW - Genome-wide association study

Genome- and phenome-wide analyses of cardiac conduction ...

Phenome‐wide association studies: a new method for ...

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In one study, genetic risk scores using thousands of SNPs derived from GWAS of psychiatric traits were able to distinguish extremes across phenotypes for ∼50 traits in the ‘behavioral phenome’ in 3152 individuals (Krapohl et al. 2016), although the effect sizes were still small (< 2% of total variance). This study also highlights the ...

Phenome‐wide association studies: a new method for ...

Ryan Irvin, PhD, MS - soph.uab.edu

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2014 Study Section, Ad hoc Member, Cardiovascular Genome Phenome Study Review Panel, American Heart Association 2016 Study Section, Ad hoc Member, Cardiovascular Genome Phenome Study Review Panel, American Heart Association 2016 – 2017 Study Section, Ad hoc Member, VA Epidemiology Research Program (EPID) 3..

Ryan Irvin, PhD, MS - soph.uab.edu

Ron Korstanje, Ph.D., FAHA - The Jackson Laboratory

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P50 GM076468, NIH/NIGMS Genome Dynamics: Evolution, Organization and Function Role: Project Leader. U54 HG006332, NIH/NHGRI The Jackson Laboratory KOMP2 Phenotyping Center Role: Domain Expert. AHA Cardiovascular Genome Phenome Study, Integrated genetic, transcriptomic, and epigenetic analysis of cardiovascular disease phenotypes.

Ron Korstanje, Ph.D., FAHA - The Jackson Laboratory

Genome- and phenome-wide analyses of cardiac conduction ...

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Genome- and phenome-wide analyses of cardiac conduction identifies markers of arrhythmia risk

Genome- and phenome-wide analyses of cardiac conduction ...

Biobanking across the phenome - at the center of chronic ...

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11/25/2013 · Recognized public health relevant risk factors such as obesity, physical inactivity, smoking or air pollution are common to many non-communicable diseases (NCDs). NCDs cluster and co-morbidities increase in parallel to age. Pleiotropic genes and genetic variants have been identified by genome-wide association studies (GWAS) linking NCD entities hitherto thought to be distant in etiology.

Biobanking across the phenome - at the center of chronic ...

Nancy Brown - True Health Initiative

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12/13/2017 · Nancy Brown has been Chief Executive Officer of the American Heart Association (AHA) since 2009. The Association is widely known and highly respected as the world’s largest voluntary health organization dedicated to preventing, treating and defeating cardiovascular diseases and stroke.

Nancy Brown - True Health Initiative

Institute for Precision Cardiovascular Medicine Funding ...

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Our first foray into the precision medicine arena was built around the Cardiovascular Genome-Phenome Study (CVGPS). Through this program, the American Heart Association (AHA) spearheaded a collaborative effort to accelerate the future of cardiovascular medicine.

Institute for Precision Cardiovascular Medicine Funding ...

Genetic variant might be a better marker for heart disease ...

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The study was supported by funding from the American Heart Association Cardiovascular Genome-Phenome Study (15CVGPSD27020012), and the authors …

Genetic variant might be a better marker for heart disease ...

Where Genome Meets Phenome: Rationale for Integrating ...

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7/24/2012 · This review provides the rationale for integrating genomic and protein biomarkers in the evolving diagnosis and management of dilated cardiomyopathy (DCM) and its causal pathway to heart failure (HF), with a larger objective to serve as a template for genomic and phenomic profiling of other cardiovascular disease. ... Phenome, Genome, and ...

Where Genome Meets Phenome: Rationale for Integrating ...

Cardiovascular Related Resources - The Jackson Laboratory

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8/1/2018 · Cardiovascular. Research focuses on various aspects of cardiovascular function, from early development to the role of genetics in determining cholesterol levels.

Cardiovascular Related Resources - The Jackson Laboratory

Jackson Heart Study > Return Of Results Workshop

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In the JHS, he serves as PI for the Coordinating Center and Field Center and as a liaison to JHS national research collaborations, including JHS Vanguard Centers, AHA Cardiovascular Genome Phenome Study, TOPMed, and other cross-cohort collaborations.

Jackson Heart Study > Return Of Results Workshop

Genome- and Phenome-Wide Analyses of Cardiac Conduction ...

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A genome-wide association study (GWAS) was performed to identify genomic markers of QRS duration in 5,272 individuals without cardiac disease selected from EMR algorithms at five sites in the Electronic Medical Records and Genomics (eMERGE) network. The most significant loci were evaluated within ...

Genome- and Phenome-Wide Analyses of Cardiac Conduction ...

(PDF) Genome- and Phenome-Wide Analyses of Cardiac ...

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The major new finding here is that using the PheWAS Chr indicates chromosome; and SNP single-nucleotide polymorphism. study paradigm, we were able to examine the longitudinal For each SNP displayed, all phenome-wide association study associations associations of these genomic variants on disease in a hypoth- P<0.01 are displayed.

(PDF) Genome- and Phenome-Wide Analyses of Cardiac ...

Van Eyk Awarded AHA Grant for Heart Study - Cedars-Sinai

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Van Eyk Awarded AHA Grant for Heart Study. Share. Email. ... The award is part of the American Heart Association's Cardiovascular Genome-Phenome Study program, which funds research to accelerate the discovery of personalized treatments and prevention of cardiovascular diseases. The program enables researchers to simultaneously access massive ...

Van Eyk Awarded AHA Grant for Heart Study - Cedars-Sinai

BN phenome: detailed characterization of the ...

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genome. Indeed, there has even been a call for the development of mouse (6) and human (11) phenome projects. Given the need to annotate the human genome with function, linking the rat into this process is a logical and necessary requirement for accelerating improvements in health care, as virtually every drug is tested in the rat before human.

BN phenome: detailed characterization of the ...
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